Aug
09
2008

20 disease specific stem cell lines created

20 types of diseased cells produced via stem cells

Using the new induced pluripotent stem cell (iPS) technique, researchers from Harvard Stem Cell Institute produced a robust new collection of disease-specific stem cell lines. Having these disease-specific iPS cells will allow researchers to watch the development of diseases in petri dishes, outside of the patients. HSCI iPS Core will produce these disease-specific cell lines for use by scientists around the world.

The cell lines the researchers produced carry the genes or genetic components for 10 different diseases, including Parkinson’s Disease, Type I diabetes, Huntington’s Disease, Down Syndrome, a form of combined immunodeficiency (“Bubble Boy’s Disease”), Lesch-Nyhan syndrome, Gaucher’s Disease, and two forms of Muscular Dystrophy, among others. Havard Stem Cell Institute Spotlight

Read the research paper online

The work is described in a paper published in the online edition of the journal Cell. Click here to read the full text of the paper titled, Disease-Specific Induced Pluripotent Stem Cells.The chief researchers were George Q. Daley, associate director of the Stem Cell Program at Children's Hospital Boston, and Chad Cowan and Konrad Hochedlinger of Massachusetts General Hospital.

Learn more by listening to their press conference

Click hear to listen to an 08/06/08 press conference with George Daley and Doug Melton (who is also co-chairman of Harvard's new interfaculty Department of Stem Cell and Regenerative Biology).

No votes yet

Post new comment

The content of this field is kept private and will not be shown publicly.
  • Allowed HTML tags: <a> <h3> <h4> <em> <i> <strong> <b> <span> <ul> <ol> <li> <blockquote> <object> <embed> <param> <sub> <sup>
  • Lines and paragraphs break automatically.
  • You may embed videos from the following providers vimeo, youtube. Just add the video URL to your textarea in the place where you would like the video to appear, i.e. http://www.youtube.com/watch?v=pw0jmvdh.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Images can be added to this post.

More information about formatting options