Stories tagged Scientific Inquiry

Feb
16
2010

What's wrong with Tut?: CT scans and DNA tests conducted over the past two years have uncovered several major problems that contributed to King Tut's death: malaria, broken leg, a club foot and restricted blood flow to Tut's left foot.
What's wrong with Tut?: CT scans and DNA tests conducted over the past two years have uncovered several major problems that contributed to King Tut's death: malaria, broken leg, a club foot and restricted blood flow to Tut's left foot.Courtesy Sanandreas
Being a boy king of Egypt had it’s share of downs along with all the gold and glitter.

CT scans and DNA testing conducted on the mummy to King Tutankhamun (King Tut for short) show that the boy pharaoh was suffering from several medical problems at the time of his death at age 19.

The contemporary medical testing shows that Tut had a cleft palate and a club foot and was suffering from malaria and a broken leg at the time that he died some 3,300 years ago. The results were announced today and will be published Wednesday in the Journal of the American Medical Association.

Medical experts have also been able to untangle the web of intrigue as to who Tut’s parents were, sort of. DNA shows that Tut is the son of the previous pharaoh, Akhenaten, and his likely mother is an unidentified sister of Akhenaten. In total, 16 mummies underwent CT scanning to get a better picture of who Tut was and what the times were like when he was alive.

The 21st Century testing was able to answer more than half of Tut’s paternity questions by identifying his father. And while we know that Akhenaten’s sister was Tut’s mother, her mummified remains confirm Tut’s DNA, her identity is still unknown. It was not uncommon in New Kingdom Egypt for pharaohs to marry to their sisters.

The findings put to bed once and for all long-held speculation that Tut was murdered. That idea was fueled by a hole in his skull, but a 2005 scan of Tut’s mummy showed that hole was made as part of the mummification process.

The majesty that we associated with Tut based on the ornate furnishings found in his burial chamber may be a far cry from what life was like for the finals days of the boy king. The medical testing shows that Tut was a sickly teen who was done in by complications from the broken leg and malaria in his brain.

On top of that, Tut had a club foot that likely required him to use a cane. In fact, 130 canes or walking sticks have been found among his burial goods, with some of the canes showing wear and tear. Tut also suffered from Kohler's disease in which lack of blood flow was slowly destroying the bones of his left foot.

Another theory cleared up through the medical tests: Tut did not suffer from any medical conditions that would have given him female body characteristics or misshapen bones.

Want to learn more? Here’s a Q&A with Egyptologist Zahi Hawass, secretary general of Egypt's Supreme Council of Antiquities, about the new Tut findings.

And here is even more in-depth coverage from National Geographic.

Bummed out that Tut was so sickly and need a pick-me-up? Do you really need a shot of Steve Martin's "King Tut" song right now? Enjoy (with a special guest appearance by Fonzie [aka Henry Winkler]). Maybe Steve needs to add a new verse to include all this new medical information.

Feb
14
2010

Naked Mole Rat: a mighty survivor both hairless and nearly blind
Naked Mole Rat: a mighty survivor both hairless and nearly blindCourtesy MissTessmacher
The naked mole rat (Heterocephalus glaber) is truly one of the most remarkable animals on this earth. On average 3 inches long and weighing just over an ounce, one would not think this creature so high and mighty. However, its unusual traits have brought it under more medical scrutiny and established an ever increasing presence in research laboratories. Stories have rung for years about how the only species to survive a world Armageddon would be cockroaches and rats. My money is on the naked mole rat.

While called a rat, they are one of 37 species of mole rats globally and are more closely related to guinea pigs and porcupines than other Rodentia. Limited to parts of East Africa, they spend their lives under ground in a highly social commune of individuals, all governed by a queen. This is very similar to the eusociality seen in bees and ants. The queen is the only female to breed, with all other individuals serving as guards or workers. This unusual social life for a mammal in a colony can lead to fierce competitions among females when the old queen dies. It may take days or weeks of power struggle before life in the colony returns to normal.

In search of plant tubers for sustenance, they dig through the dirt with their teeth, developing a system of burrows that can carry on for miles. One of the naked mole rats remarkable features is its ability to survive in the high carbon dioxide environments of these tunnels. Their extremely low metabolic rate and high absorption of oxygen allow them to overcome the limitations of the cramped and congested space. Research has found that these mole rats are void of a pain transmitter called Substance P found in other mammals, and have an uncanny resistance to the oxidative stress of daily metabolism.

Researchers hope this could lead to new insights into the process of aging. Captive research colonies have had individuals live as long as 28 years. That is more than nine times as long as a research mouse! This longevity and unique durability lead even more scientists to consider the naked mole rat for captive study populations in the fight against other afflictions like stroke and cancer. If these superman-like traits haven’t given you a deeper appreciation for such a tiny hairless creature, perhaps you just need a clever ditty to sing their praises. Oh! …you so UGLY!

Feb
08
2010

Measuring the SMM camptosaurus: SMM paleo lab volunteers Becky Huset (left) and Neva Key consult over their ornithischian limb bone measurements for the Open Dinosaur Project.
Measuring the SMM camptosaurus: SMM paleo lab volunteers Becky Huset (left) and Neva Key consult over their ornithischian limb bone measurements for the Open Dinosaur Project.Courtesy Mark Ryan
The Open Dinosaur Project (ODP) allows anyone with an interest in paleontology, and access to skeletal information, scientific publications, or museum skeletons themselves the opportunity to be part of the compilation of an actual scientific paper. Paleontologists Andy Farke, Matt Wedel, and Mike Taylor make up the core ODP team, but only the core. The rest of the team is made up of individuals around the world. The hope is to put together a comprehensive database of information about the dimensions of limb bones (legs, arms, hands, and feet) of ornithischian (bird-hipped) dinosaurs in museums around the world with a goal of “investigating the evolution of locomotion and limb proportions in this group.”

“The Open Dinosaur Project fits very comfortably into that loose coalition of ideas: we’re trying to democratize science, open up data, blog the process, and make sure that the final publications are freely available to the world,” Mike Taylor said during a recent interview with the Brazilian science publication Ciência Hoje On-line.

Putting tape to toe: SMM volunteer Becky Huset measures the metatarsals and phalanx of the musuem's camptosaurus for the Open Dinosaur Project.
Putting tape to toe: SMM volunteer Becky Huset measures the metatarsals and phalanx of the musuem's camptosaurus for the Open Dinosaur Project.Courtesy Mark Ryan
Two volunteers here at the Science Museum of Minnesota got themselves involved with this unique study. Becky Huset and Neva Key both work in the SMM paleo lab, usually hunched over fossils extracting them from rocks or preparing them for display. But recently, the two have spent time out on gallery floor measuring the limbs of some of the museum’s mounted ornithischian dinosaurs.

“We did the Camptosaurus and some cast bones from Stegosaurus from the collections,” Becky said. She added that measurements of the SMM Triceratops were already listed.

Why only ornithischian dinosaurs? Part of the reason was to keep the study somewhat manageable. But ornithischian dinosaurs also have an interesting evolution of locomotion that to date hasn’t been studied in depth. The dinosaur order radiated from a two-legged (biped) form into at least three different four-legged (quadruped) forms including armored dinosaurs (e.g. stegosaurs and ankylosaurs), ceratopsians (e.g. triceratops and chasmosaurus), and various ornithopod types, (e.g. camptosaurs, hadrosaurs, and iguanodontids).

How to measure a scapcoracoid: One of several measuring aids available to project volunteers from the Open Dinosaur Project website.
How to measure a scapcoracoid: One of several measuring aids available to project volunteers from the Open Dinosaur Project website.Courtesy Open Dinosaur Project
In order to aid team members in gathering the proper information, instructions, templates, and other documents are available on the Open Dinosaur Project website. Diagrams explaining ornithischian limb osteology – including each bone’s proper name - are also on the site, as are illustrations showing exactly how to properly measure the dimensions of different bones. For those involved who don’t have access to museum specimens or material in other collections, the team leaders provide lists where prior publications with skeletal information can be accessed and mined for the study.

By last week, the Open Dinosaur Project had acquired nearly 1600 entries, but the results of all this work remain to be seen. The compiled data will be analyzed over the next couple months, and Farke, Wedel, and Taylor plan to begin writing the paper this spring. When completed the study will be submitted for publication in a peer-reviewed journal. If all goes as planned, after publication, the lead researchers will make all the data available online for future studies.

Now that their data has been entered on the ODP site, SMM volunteers Huset and Key will have their names included as contributors, and eligible to be included in the resulting paper.

"We wanted to get the general public excited about and involved in doing “real” science, working in cooperation with paleontologists. There is a great interest out there in paleontology, particularly dinosaurs. It’s amazing how many non-paleontologists read the technical literature! I thought, “Why not harness this enthusiasm?” There have been many people waiting for this sort of opportunity (even if they didn’t know it), and I think the response speaks for itself." – Andy Farke in Ciência Hoje On-line

Becky Huset enjoyed being involved with the project. “[It] sounded like a good idea,” she said. “I like having knowledge that is freely available to everyone, and it was a good way to contribute to a paper. Do some "real" work."

LINKS

Open Dinosaur Project website
Wedel’s & Taylor’s dino-related blog
More about Ornithischian dinosaurs
Osteology (the scientific study of bones)

Feb
08
2010

The Discovery of King Tut: Howard Carter, staging the discovery of King Tut, in 1922.
The Discovery of King Tut: Howard Carter, staging the discovery of King Tut, in 1922.Courtesy Wiki Media Commons
Science Buzz bloggers have been buzzing about this topic for some time, but as the time draws near, I thought I would jump in for those new to Science Buzz. The rapidly expanding field of DNA analysis is now being used to verify the genealogy of the great kings of Egypt. Zahi Hawass, chief of the Supreme Council of Antiquities in Egypt, has announced that on February 17th, 2010 he will be revealing the results of DNA testing on the famous mummy of the boy king, Tutankhamun. DNA testing has already been done on King Amenhotep III (who reigned from approximately 1388 to 1351 BCE) for comparison as he is believed to be either Tut’s father or grandfather. The mummy of Amenhotep’s son, Akhenaten (who could be Tut’s father), has yet to be found. Researchers also plan to test the DNA of two mummified fetuses found in the tomb to determine if they are related to Tut and shed light on whether King Tut’s bride, daughter of Akhenaten, was his full sister or half sister.

Despite the popularity of King Tut and the splendid artifacts found in his tomb, he is actually only a minor figure in the history of Egyptian pharaohs, reigning for a mere 10 years in a time of great unrest. The story of Akhenaten is more interesting. Akhenaten, who ruled from 1352 to 1336 BCE, is famous for changing both religion and artistic style in Egypt, what is now known as the Amarna Period. Akhenaton introduced a new monotheistic cult of worship surrounding the sun disc Aten and excluded all other Egyptian gods from being worshipped in an effort to suppress the powerful priesthood of Amun.

Pharaoh Akhenaten: Classic Amarna Period sculpture of the Pharaoh Akhenaten.
Pharaoh Akhenaten: Classic Amarna Period sculpture of the Pharaoh Akhenaten.Courtesy Hajor and Wiki Media Commons
Artwork during the Amarna Period took on a more naturalistic style and often emphasized affectionate family scenes of the Pharaoh with his wife Nefertiti and their children. Of interest to many art historians is the depiction of Akhenaten himself. He is represented with an accentuated feminine appearance, rounded protruding belly, wide hips, long slender limbs, and a long thin face. Some believe it is a purposeful political depiction stressing his belief in equality of the sexes, some suggest he was a hermaphrodite, and others suggest he had Marfan’s syndrome. People with Marfan’s syndrome are usually very tall with long thin arms and legs, have thin faces, and funnel shaped chests. Unfortunately, until his mummy is located this will remain a mystery.

When Akhenaten died, the priests of Amun regained power, striking Akhenaten’s name from Egyptian records, reversed all of his religious and governmental changes, and returned the capitol to Thebes. His son, Tutankhaten changed his name to Tutankhamun to honor Amun and became the now famous boy king ruling from 1336 to 1327 BCE.

Mr. Hawass has announced plans to test all the royal mummies using their new $5 million DNA lab in the Egyptian museum. However, there is some concern in the scientific field that he will not submit results to labs outside Egypt for independent verification as is common practice in DNA testing. For example, DNA results of Hatshepsut, Egypt’s famous, powerful and only female pharaoh have never been released. Our fascination with the pharaohs is sure to continue for many more centuries.

Feb
08
2010

Viral hemorrhagic septicemia: a fish infected with the virus
Viral hemorrhagic septicemia: a fish infected with the virusCourtesy Dr. Mohamed Faisal
No… not a rock bass (even though it has a red iris). Nor any normal walleye you might be lucky enough to snag. This fish you might not even need to actually catch. It could be floating next to the boat along with most of the other fish in your favorite river, lake, or reservoir. That is if the dreaded VHS continues to spread and strike us deep in the land of 10,000 lakes. Move over zebra mussel, Eurasian milfoil, and the Asian carp, VHS is viral hemorrhagic septicemia and the latest migrant in the spread of invasive species.

Viral hemorrhagic septicemia (VHS) is a virus. It is a small invading critter that can be quite infectious. Not all fish will show obvious signs. Those that do can exhibit hemorrhaging in the eyes, around the fins, or on the gills. Bloating, erratic behavior, bulging eyes, or even lesions could also be present. On the inside, the disease will attack the liver, kidneys, spleen or swim bladder. Those fish that do survive can still be infected and spread the disease. Blood, urine and even the reproductive fluids of infected fish can pass on the virus. Larger fish can get it from eating smaller infected fish.
Fish kill: sights like this are all the more possible with the new viral invader
Fish kill: sights like this are all the more possible with the new viral invaderCourtesy JoelDeluxe

The disease can be wide spread and is known to affect up to 28 different species of fish. Some of the fish kills have numbered in the tens of thousands. Many of our popular game fish are susceptible. Walleye, Northern Pike, Muskellunge, Smallmouth Bass, Perch, Crappies, Bluegills, Sheepshead and many others are on the list. Even some species of shiner bait fish have been found to carry the disease. While deadly for many fish, the disease is of no harm to humans. The warmth of our bodies is too hot for the virus to survive.

The virus has been known for many decades, but until recently was mainly a scourge of European fish farms. Viral hemorrhagic septicemia was first detected in American coastal waters in 1988, among the salmon populations of the Pacific Northwest. Then in 2005, tested fish showed up positive between Lake Huron and Lake Erie, and were confirmed in samples harvested two years earlier. Now, local news just recently reported on a Cornell study that found VHS diseased fish in the bay waters of the Duluth-Superior harbor on the western edges of Lake Superior. Make no mistake… the ‘bleeding fish’ disease is here at our doorstep.

Guests of the inland waterways will be reminded to be vigilant in safe boating and fishing practices by local resource managers. Be mindful not to transport fish, plants, or bait from one water body to another. Keep those live-wells empty, and dry or rinse that boat! It will fall upon all of us to remain vigilant. Let’s not allow this disease to become a crippling blow to our native fisheries. If we do, it is possible that we’ll witness many seasons of massive fish kills.

More good VHS information:
Wisconsin Dept. of Natural Resources

Univ. of Wisconsin Sea Grant

Feb
01
2010

hamburger: what is it really made from?
hamburger: what is it really made from?Courtesy PixelAndInk
No fries. I’m watching my diet.

Yeah, I said ammonia burger. Haven’t you heard that your favorite fast food beef gut –bomb was most likely treated with ammonia? It’s not like the teenage fry cook at the burger joint reaches under the counter and grabs the bottle of floor cleaner to splash on a sizzling grill. However, there is still extra ammonia used to treat a ‘portion’ of your burger. Just a little extra ammonia injected during a specially patented process that makes up a percentage of the meat to form a patty. That ‘portion’ is where I think the real story lies.

Over the last few months, the news wires have been releasing stories about this specially patented process, including leading breaks by the New York Times. The stories center on the company, Beef Products Inc. (BPI) located in South Dakota. BPI developed the procedure of treating beef trimmings with ammonia to reduce the presence of harmful bacteria such as salmonella and E. Coli. Some of their main customers include McDonald’s, Burger King, and local food conglomerate Cargill. BPI had performed so well during USDA inspections that by 2007 they were exempted from testing. Its customers have stood firmly by its side. Last summer, things changed when school outbreaks of salmonella resulted in a banning of BPI meat products in some states. The pressure is on the U.S. Department of Agriculture now to investigate any issues.

No one wants to eat meat products contaminated with E. Coli or salmonella. But the whole idea of eating something treated with ammonia just doesn’t sound safe. Was it too many years of Mr. Yuck stickers as a child? I realize ammonia is a naturally occurring substance and can be already present in meats. When I really began to search my inner self about this angst, I found that what truly bothered me was the product being treated. This ammonia process wasn’t used on all beef. Slaughterhouses don’t give the fated bovines an ammonia bath before packaging. This process only is used on beef trimmings. Just say those two words to yourself slowly… pause and contemplate. Beef Trimmings.

raw ground meat?: i'd guess that the pink slime is what holds it together.
raw ground meat?: i'd guess that the pink slime is what holds it together.Courtesy cobalt123
Described by one source as a “pink slime”, trimmings are the last vestiges of muscle tissue left from a good butchering. It has been separated from the ‘majority’ of bone, cartilage and connective tissue. It is then spun by centrifugal force to remove fat, pressed, screened for metal, frozen, chipped, and pressed into 60 pound blocks. In the end, it only need be 12% visible lean tissue to classify as trimmings. The USDA has standards on what constitutes both meat and trimmings. This scrap used to be regulated to pet food and cooking oil. Do we really need to be mixing some into each of our double cheeseburgers? I’d be curious to know what percentage of trimmings makes up that quarter pound patty. Take out the trimmings and we can skip the whole ammonia question.

Recent questions are being plumbed by many parties about these food safety issues. Requests for documents have been met with some resistance by BPI. They seek to block any release of the research done by the Iowa State professor who published supportive findings. Now the courtroom waltzes begin and the delay of answers drags on. I’m certain this won’t be the last we’ve heard of those tasty ammonia treated trimmings.

I think i'll change that order to a chicken sandwich. That's 'free-range' correct?

Jan
28
2010

Sinosauropteryx
SinosauropteryxCourtesy Chuang Zhao and Lida Xing
Scientists from China and the United Kingdom say they have found hints of color present in the fossils of both an ancient bird called Confuciusornis and a non-avian dinosaur called Sinosauropteryx. Using an electron microscope the researchers detected differently-shaped organelles called melanosomes in the feathers of each creature. Melanosomes contain melanin which determines color in human hair, animal fur, and feathers, but it's the shape of the melanosomes that determine the shade.

"A ginger-haired person would have more spherical melanosomes, and a black-haired or grey-haired person would have more of the sausage-shaped structures," said Mike Benton, professor of paleontology at the University of Bristol, and leader of the study.

Both shapes were found in the remains of Confuciusornis, which lived during the Early Cretaceous period. In the Sinosauropteryx fossil, which dates back to the same time, light and dark bands visible along its tail were determined to be white and ginger in color when its fossilized melanosomes were viewed under the microscope. The presence of melanosomes also confirms that the turkey-sized dinosaur had actual feathers rather than just shredded connective tissue as some scientists have suggested. The research appears in the latest issue of Nature.

Watch an interview with Professor Benton.

SOURCES
University of Bristol page
BBC story

Jan
21
2010

Removing plant oil: Ok, she isnt removing plant oil from a Dead Sea Scroll, but this is how I imagine it would look when they eventually do.
Removing plant oil: Ok, she isnt removing plant oil from a Dead Sea Scroll, but this is how I imagine it would look when they eventually do.Courtesy Walters Art Museum
The Dead Sea Scrolls have been radiocarbon dated two different times since they were discovered (excludiing the test on a piece of linen associated with the scrolls in the 1950’s by Willard Libby(the guy who invented the radiocarbon dating method)) by the Zurich Institute of Technology (1990) and the University of Arizona (1994). From these tests, researchers concluded that the scrolls are roughly 2,000 years old. However, scientists now think they can take “roughly” out of the picture, and provide more precise dates for the origins of the scrolls.

How would they do this? Is there a brand new method used for dating ancient objects?! Umm…no. Scientists will still use carbon-14 dating, but they found that a good ol’ scrub before the dating process provides better results (that usually holds true for people, too). I don’t mean that they’ll use soap and water (that would probably not be a good idea), but rather a chemical to remove plant residue. What happened was that in order to unroll the scrolls and spread them out without pulverizing them, researchers treated the scrolls with plant oil. This oil is thought to have interfered with the carbon-14 dating.

But now, after more than ten years of lab work, archaeochemist Kaare Lund Rasmussen and his team of researchers have developed a chemical that will remove the plant oil without harming the scrolls themselves. With this residue gone, the Dead Sea Scrolls can be more precisely dated, and history can be more accurately written (if you subscribe to the “accuracy” of history). At this point, there has been no new round of tests on the scrolls, and it’s unclear when that will take place.

Jan
04
2010

I was surfing around the web the other night and came upon some a series of new videos on YouTube documenting a program originating out of the Paleon Museum in Glenrock, Wyoming. If you want to hunt for dinosaur fossils, Wyoming is the place to go. The series of videos follow a crew of paleo-wannabees led by museum director, Sean Smith, to a couple nearby dig sites. Renowned paleontologist Bob Bakker also gets involved, adding knowledge and background facts, and helping the participants decipher what exactly they find.

The program is well done and contains pretty much what you’d expect on the subject, but what’s cool about this particular series is that one of the participants involved was a volunteer here at the Science Museum of Minnesota a couple years ago. Katie Grace worked with me in the Dinosaur and Fossils gallery, and I remember talking with her about the summer adventure she had with her dad looking for dinosaurs in Wyoming.

Katie appears throughout the videos but most prominently in Pt. 1 where she is interviewed starting at 7:10. Way to go Katie!

By the way, the last video in the series features several watercolor paintings by geologist Arthur Lakes, a subject I wrote about a couple weeks ago.

Dec
30
2009

The sky's the limit!: But probably not for this group; they look more like posers than actual paper airplane aficionados.
The sky's the limit!: But probably not for this group; they look more like posers than actual paper airplane aficionados.Courtesy toolmantim
Here’s an article about a paper airplane virtuoso who’s trying to break the world’s record (held by himself) for keeping a hand-launched paper plane in the air. Engineer Takuo Toda of Japan not only wants to beat his old record of 27.9 seconds – set last April in Hiroshima – he’s also set his sights on achieving the nearly impossible - breaking the 30 second barrier. Actually, the record time of 27.9 seconds should require an asterisk in the record books since it was set using a paper plane with tape on it. The paper-only airplane record – using a single sheet of uncut paper - is 26.1 seconds, and Toda holds that one, too. This guy seems to be the undisputed king of paper airplanes, but I'm sure somebody out there can show him a thing or two. Check out some of the links below and maybe it can be you.

MORE ABOUT PAPER AIRPLANES
More about paper airplane aerodynamics
Build your own paper airplane (by former record holder Ken Blackburn
Build the best paper airplane
How to build 10 paper airplanes with animated instructions no less
Even more paper airplane designs