“Replacement bladder”? Try “extra bladder.”

Another day at the lab: Not exactly a "clean room," but it does the trick.
Another day at the lab: Not exactly a "clean room," but it does the trick.Courtesy phil dokas
These days it’s all about growing organs. Like the Frankenrat hearts, remember?

Don’t get me wrong, growing hearts from scratch is great, but, really, what am I supposed to do with an extra heart? Frame it? Bo, grow me an organ I can use now, and we’ll talk. That’s why I’m getting into this little development: replacement bladders. Or, as I like to call them, extra bladders.

Turn that one over in your braincase. You’re engaged in one of the countless activities during which you don’t want to be peeing (watching a movie, taking a bath, wrestling a bully) and all of a sudden…you’re full to the point of overflowing. How did that happen? It was all that Gatorade—those bottles are so big! But no probs, just switch to the auxiliary tank. Or, you know, if you lost your bladder to cancer. Then it would be pretty nice too.

The process for growing the bladders is sort of similar to the heart-growing linked to above. Progenitor cells from the recipient’s old bladder are grown in a culture, and then seeded to an organic frame—a bladder-shaped scaffold made from collagen. Once the tissue grows over the scaffold, the whole thing is implanted into the recipient.

The procedure has been tested on 14 large mammals, and within six months the new bladder seems to work pretty much the same as the original, with no abnormal tissue growth, or signs of rejection from the host body.

I can hardly wait.

Your Comments, Thoughts, Questions, Ideas

hmoob_muas's picture
hmoob_muas says:

i want one extra bladder, just incase..

posted on Thu, 05/22/2008 - 8:57am
BLB's picture
BLB says:

I dont think it can ever get that serious for someone to get an extra bladder, unless they lost it or have an infection....


posted on Thu, 05/22/2008 - 9:07am
Candice_318's picture
Candice_318 says:

Wow wear a diaper and call it a day... Saves you a lot of money on your??? whatever But it saves you money aight

posted on Thu, 05/22/2008 - 9:11am
nelson.robin's picture
nelson.robin says:


posted on Thu, 05/22/2008 - 9:14am
shanee's picture
shanee says: extra bladder! thats crazy..

posted on Thu, 05/22/2008 - 9:15am
MrBig621188's picture
MrBig621188 says:

eventually those diapers threw out a long period time could add up to the extra bladder and besides just pause the movie or what ever call a time out and take go to the bathroom. ( and if you are wrestling bullies well good luck with that one.)

posted on Thu, 05/22/2008 - 9:16am
twila_08's picture
twila_08 says:

I think that this will be nice. Because I never get up right away when I have to pee. I wait awhile it's a little harder for females.

Twila Turnage

posted on Thu, 05/22/2008 - 9:21am
diamond2008's picture
diamond2008 says:

wow a new invention nice!!

posted on Fri, 05/23/2008 - 8:49am
Anonymous's picture
Anonymous says:

Does anyone know where this is being done (on human beings)in or around the Boston area? My father has bladder cancer and will likely need his bladder removed. Any information would be appreciated.

posted on Sun, 06/15/2008 - 7:24pm
JGordon's picture
JGordon says:

I think research into regenerative medicine is being done at quite a few institutions, but I'm pretty sure this particular story came out of a company called Tengion in NC.

It looks like human trials are planned for 2009.

posted on Mon, 06/16/2008 - 8:15am
Anonymous's picture
Anonymous says:

To some it may be a joke. To many, its a matter of life and death. Does anyone know where updates on current research can be found? Specifically I want to know if experiments on livers have been carried out. If this reseeding/regrowing is going to work then surely the liver is the major one to try?

posted on Wed, 04/22/2009 - 1:45pm

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