Stories tagged stemagen

Jan
22
2008

Human embryos using animal eggs

Embryo, 8 cells
Embryo, 8 cellsCourtesy Ekem
Last week we learned that scientists cloned human embryos using adult skin and fertile eggs from a woman donor. Now the Human Fertilization and Embryology Authority in Britain has approved creating human embryos using eggs from animals like cows or rabbits. Because the animal cell's nucleus would be removed before human DNA was added, scientists said the resulting egg would not be a chimera.

"Cow eggs seem to be every bit as good at doing this job as human eggs," said Lyle Armstrong of Newcastle University.
"We will only use them as a scientific tool and we need not worry about cells being derived from them ever being used to treat human diseases," Armstrong said.

Technique eliminates destruction of human eggs

Animal eggs are abundant and easily obtained. Researchers hope to refine their techniques by practicing first on animal eggs to producing human stem cells. Human stem cells, which have the ability to develop into any cell in the human body, show promise for understanding and healing many human ailments. The embryos would not be allowed to develop for more than two weeks.

Jan
18
2008

Blastocyst day 5
Blastocyst day 5Courtesy Ekem

DNA from clone identical to that from adult skin donor

A paper published in the online journal, Stem Cells, yesterday titled "Development of Human cloned Blastocysts Following Somatic Cell Nuclear Transfer (SCNT) with Adult Fibroblasts" is the first documented demonstration that ordinary cells from an adult human can be used to make cloned embryos mature enough to produce stem cells

"A research team at Stemagen, a biotech company based in San Diego, California, started with skin cells donated by two men and 25 eggs, or oocytes, donated by women at a nearby fertility center. The scientists removed the DNA-containing nuclei from the eggs and replaced them with DNA from the donor skin cells. Two of the eggs became 5-day-old embryos, or blastocysts, that were clones of the male donors."Science

Why are we cloning humans?

The next big step will be to create a human embryonic stem cell line from cloned embryos. Stem cells from cloned embryos could provide a valuable tool for studying diseases, screening drugs, and creating transplant material to treat conditions like diabetes and Parkinson's disease.

Should we be doing this?

As expected, critics are raising objections. This procedure requires cutting healthy eggs out of women, then altering them to produce living embryos, which are then destroyed. Should this be allowed?

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